You may have noticed that what is new often behaves differently than what has become accepted over time, whether it is in a market, or a technology, or involves people and firms. Much research supports this general idea. This course brings that perspective to the topic of managing innovation. That is, how do you lead and design your organization to effectively implement innovation initiatives and achieve the strategic intent? This interesting and important challenge is the central focus of our course. We start the course by examining how to successfully implement innovation efforts within established firms and alongside established businesses. We then move to the particular challenges of managing where disruptive technologies are involved. Next, we delve into leadership of new product development teams. We take a look at how planning and evaluation must be different, but still can be effective in innovation situations. Finally, we examine how to manage innovation when the effort spans organizational boundaries, as with alliances or virtual firms. Throughout the course, the goal is to offer a set of frameworks, tools, and concepts that can help participants build their skills in leading innovation initiatives effectively.