Acerca de este Curso

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Fechas límite flexibles
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Aprox. 95 horas para completar
Inglés (English)
Certificado para compartir
Obtén un certificado al finalizar
100 % en línea
Comienza de inmediato y aprende a tu propio ritmo.
Fechas límite flexibles
Restablece las fechas límite en función de tus horarios.
Nivel intermedio
Aprox. 95 horas para completar
Inglés (English)

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Universidad Johns Hopkins

Programa - Qué aprenderás en este curso

Semana
1

Semana 1

75 horas para completar

Module 1

75 horas para completar
10 videos (Total 121 minutos), 3 lecturas, 1 cuestionario
10 videos
Course Introduction16m
Introduction49s
Center for Alternatives to Animal Testing4m
Toxicology of the Fifteenth to Twentieth Centuries15m
Toxicology for the Twenty-First Century15m
Historical Perspective17m
The First Report: Toxicity Testing for Assessment of Environmental Agents11m
The Second Report: Toxicity Testing in the 21st Century: A Vision and A Strategy Vision and Its Components22m
The Second Report: Toxicity Testing in the 21st Century: A vision and A Strategy Implementation13m
3 lecturas
useful links20m
supporting reading material10m
Supporting reading material10m
1 ejercicio de práctica
Module 1 Quizs
Semana
2

Semana 2

4 horas para completar

Module 2

4 horas para completar
10 videos (Total 119 minutos), 4 lecturas, 2 cuestionarios
10 videos
Adverse Outcome Pathways (AOPs)10m
Exposure-Based Chemical Prioritization13m
ER Bioactivity Model16m
US EPA Endocrine Disruptor Screening Program (EDSP)17m
Modeling of Hazard and Organ Manifestation11m
Building a Signature for Vascular Disruption10m
Testing the Vascular Disruption Signature8m
Virtual Tissue Model: Vascular Development12m
Functional Vascular Development Assays16m
4 lecturas
Supporting Reading Material10m
Useful links10m
Supporting Reading Material10m
Useful links10m
1 ejercicio de práctica
Module 2 Quiz30m
Semana
3

Semana 3

3 horas para completar

Module 3

3 horas para completar
11 videos (Total 126 minutos), 2 lecturas, 1 cuestionario
11 videos
Mechanistic Toxicology and Pathway Mapping at the Basics of 21st Century Toxicology16m
The Concept of the Human Toxome Project21m
Concept and Tool Devlopment11m
Progress7m
Conclusions and Prospectives8m
Introduction - What Is a Pathway of Toxicity, and Why Do We Need Them?6m
Omics Technologies and High-Throughput Data11m
Interpreting Omics Data11m
PoT Examples and Conclusions15m
Pathways of Toxicity and Adverse Outcome Pathways (AOPs)13m
2 lecturas
Supporting reading materials10m
Supporting reading material10m
1 ejercicio de práctica
Module 3 Quiz30m
Semana
4

Semana 4

4 horas para completar

Module 4

4 horas para completar
15 videos (Total 148 minutos), 3 lecturas, 2 cuestionarios
15 videos
The Concept of Toxicological (Biological) Pathways, e.g., “Adverse Outcome Pathways,” Is the Basis of Predictive Toxicology5m
Introduction to the OECD AOP Framework10m
Building, Evaluating, and Using AOPs in Safety Decisions6m
Online Tools Available to Everyone, Including an Online AOP Course4m
Welcome to Module 42m
Introduction to Read-Across18m
Good Read-Across Practice21m
Supporting Read-Across with Biological Data12m
Creating a Database of Toxicity12m
Creating an Automated Tool for Read-Across9m
Paradigm Shift in Toxicology7m
2D In Vitro Cell Culture8m
3D In Vitro Cell Cultures8m
Organ-on-a-Chip11m
3 lecturas
Supporting reading material10m
Supporting reading material10m
Useful links10m
2 ejercicios de práctica
Module 4 Quiz30m
Mid-term exam30m
1 hora para completar

Module 5

1 hora para completar
6 videos (Total 41 minutos), 1 lectura, 1 cuestionario
6 videos
MicroRNA and Epigenetics4m
Epigenetics and Environment6m
MicroRNA: Biogenesis and Functions11m
Role of MicroRNA in Development6m
MicroRNA in Toxicology9m
1 lectura
Supporting reading material10m
1 ejercicio de práctica
Module 5 Quiz30m

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