About this course: Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030. Everyone has been, or will be touched by cancer in some way during their lifetime. Thanks to years of dedication and commitment to research we’ve made enormous advances in the prevention and treatment of cancer, But there is still a lot of work to be done. In this course, physicians and scientists at the Johns Hopkins School of Medicine explain how cancer spreads or metastasizes. We’ll describe the major theories of metastasis and then describe the biology behind the steps in metastasis. The course also describes the major organs targeted by metastasis and describes how metastases harm the patient.
Who is this class for: This course should be helpful to anyone who wants to develop a deeper understanding of cancer metastasis. It should be useful to undergraduate students who are interested in exploring the science of cancer and to health care providers, data managers, and educators who need a more thorough understanding of metastatic cancer and how it affects individuals. The course is NOT designed for patients seeking treatment guidance.
Taught by: Kenneth J. Pienta, M.D., The Donald S. Coffey Professor of Urology
The James Buchanan Brady Urological Institute
Taught by: Jelani Zarif, Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Taught by: Sarah Amend, Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Taught by: Haley Axelrod, Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
Taught by: Kenneth Valkenburg, Prostate Cancer Researcher
The James Buchanan Brady Urological Institute
| Level | Beginner |
| Commitment | 3 weeks, 1.5 hours per week |
| Language | English |
| How To Pass | Pass all graded assignments to complete the course. |
| User Ratings |
- Video: Introduction to Understanding Cancer Metastasis
- Video: Introduction to History and Overview of Metastasis
- Video: History and Overview of Metastasis
- Video: History of Metastasis Theory
- Video: Introduction to the Sequential Steps of Metastasis
- Video: Introduction to Primary Tumor Growth and Neoangiogenesis
- Video: Tumor formation: Uncontrolled cell division
- Video: The role of mutations in primary tumor formation and evolution
- Video: Neoangiogenesis: new blood vessel formation in cancer
- Video: The primary tumor microenvironment: what else affects primary tumor growth?
- Video: Introduction to EMT / Invasion / Intravasation
- Video: Epithelial-mesenchymal transition, invasion, and intravision
- Video: Local Tumor Invasion
- Video: Intravasation
- Video: Introduction to Survival in the Circulation and Extravasation
- Video: Glossary of Terms
- Video: The Circulation
- Video: How cancer cells survive while in circulation
- Video: Becoming a circulating tumor cell (CTC) and evading immune detection
- Video: Homing to a new site in the body and extravasation
- Video: Introduction to Dormancy and Secondary Tumor Growth
- Video: Metastatic homing
- Video: Evidence for cancer dormancy
- Video: Cancer dormancy defined
- Video: Properties of dormant cancer cells
- Video: Secondary outgrowth
- Video: Introduction to Morbidity and Mortality
- Video: Distribution of Metastasis: Where do cancers spread?
- Video: Cancer Syndromes
- Video: Congratulations
Each course is like an interactive textbook, featuring pre-recorded videos, quizzes and projects.
Connect with thousands of other learners and debate ideas, discuss course material, and get help mastering concepts.
Earn official recognition for your work, and share your success with friends, colleagues, and employers.
| Audit | Purchase Course | |
|---|---|---|
| Access to course materials | Available | Available |
| Access to graded materials | Not available | Available |
| Receive a final grade | Not available | Available |
| Earn a shareable Course Certificate | Not available | Available |
nice course
I would have enjoyed more in-depth descriptions of some of the particular processes and mechanisms described (ie, degradation of the ECM using MMPs), but I also realize that this course wasn't intended to contain that level of detail. There were a few quiz questions (about two to three in the whole course) with correct answers which I found questionable, but I am otherwise satisfied.
Very informative and concepts were explains very clearly. Thanks to all the professors who taught this course.
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MM
This course is completely informative and easily understandable for the beginners especially. Thanks to Coursera and John Hopkins University for the wonderful course.