SEMANA 1

Course Introduction

Welcome to Epidemics: the Dynamics of Infectious Diseases. This course will teach you about the variety of parasitic organisms that infect humans, animals, and plants, how these parasites spread through populations, and the various methods that we employ to control them.

3 lecturas

Reading: Course Overview
Reading: Course Syllabus
Reading: Glossary of Terms

Pathogens

In the first module, you will learn about the organisms that can infect us and make us sick: pathogens. We will first take a look at the various types of pathogens that exist, and then learn about what it means to be infectious, and what it means to cause disease. After that, we will cover the various methods by which pathogens can transmit from one person to the next, thereby causing an epidemic. You will learn about the most important number in all of epidemiology, R0, and why this number is so important. Finally, we will learn that microorganisms are not always harmful, but can be beneficial to us as well.

7 videos, 1 lectura

Reading: Module Overview
Vídeo: Micro and Macro Parasites
Vídeo: Infection and Disease
Vídeo: Transmission Types
Vídeo: Reproductive Number
Vídeo: Epidemic Curve
Vídeo: Micro-organisms

Calificado: Summative: Pathogens

SEMANA 2

Hosts

The second module of the course covers host factors that determine the outcome of infection. We will first focus on host immunity and present both the general immune capabilities—the innate immune response—that are encoded in our genes and that provide the initial response to infection and the adaptive immune response, which arises from highly specialized cells that protect against a specific pathogen. You will then learn about the ways that pathogens circumvent these two types of immunity and consider other factors that can contribute to an individual becoming infected or diseased—including genetic factors, other microbes, and how social and emotional factors influence immunity. We will then consider how infection with a microorganism causes disease and how public health officials determine whether a disease outbreak is caused by an infectious organism.

7 videos, 1 lectura

Reading: Module Overview: Hosts
Vídeo: Types of Immunity: Adaptive Immune System
Vídeo: Immune Evasion
Vídeo: Other Determinants of Susceptibility
Vídeo: Social Influences on Immunity
Vídeo: Pathogens and Disease
Vídeo: Detecting an Infectious Disease Outbreak

Calificado: Summative: Hosts

SEMANA 3

Basics of Ecology

The third module of the course covers ecological factors that influence the dynamic patterns of infectious disease. We will discuss the conditions under which a pathogen can drive its host to extinction. We will look at how the demography of the host may allow the pathogen to persist in some populations but not others. We will talk about how host and pathogen characteristics interact to shape different temporal patterns of disease incidence at the population level and discuss the ecological consequences of infecting more than one host species.

9 videos, 1 lectura

Reading: Module Overview: Basics of Ecology
Vídeo: Force of Infection
Vídeo: Cycles
Vídeo: Seasonality
Vídeo: Flu 1918
Vídeo: Host Diversity, Host Range
Vídeo: Critical Community Size
Vídeo: Pathogen-Microbiome Interactions
Vídeo: The 2014 Ebola Outbreak

Calificado: Summative: Basics of Ecology

SEMANA 4

Epidemiology

Where humans live and how they are connected to each other, have strong effects on how infectious diseases can spread. In this module, you will learn about some of the related key concepts of epidemiology. After looking at some fascinating history, we’ll learn about social networks as the ultimate “road map” on which diseases can travel and we’ll talk about how the structure of the network can influence disease dynamics. After that, we’ll cover three topics that all affect infectious disease epidemiology in dramatic ways: human transport systems, population density and so-called superspreaders - individuals who can spread a disease to dozens or even hundreds of other individuals. We’ll close by identifying what information is required for disease surveillance.

8 videos, 1 lectura

Reading: Module Overview: Epidemiology
Vídeo: Social Networks
Vídeo: Structure of Networks
Vídeo: Superspreaders
Vídeo: Spatial Hetergeneity
Vídeo: Movement and Modern Transportation
Vídeo: Surveillance and Disclosure
Vídeo: Co-Infection Consequences

Calificado: Summative: Epidemiology

SEMANA 5

Vaccination

In module 5 of the course, you will learn about vaccination, one of the most common approaches to the prevention of epidemics. We'll first put vaccination in the context of the many types of public health interventions that that can be used to prevent or treat disease. After that you will learn about the development of the first vaccine, how vaccines work to prevent infection, and the impact that vaccination has had on the prevention of disease worldwide. After that, you will learn about how vaccination can provide protection to everyone, even the unvaccinated, in the population through "herd immunity" and how we can use the structure of social networks within populations to more efficiently achieve this herd protection. Finally we'll learn about how individuals choices about whether or not to get vaccinated can lead to impacts across the whole of the population.

7 videos, 1 lectura

Reading: Module Overview: Vaccination
Vídeo: Discovery of the First Vaccine
Vídeo: Global Impact of Vaccination
Vídeo: How Vaccination Works
Vídeo: Herd Immunity
Vídeo: Social Networks and Targeted Vaccination
Vídeo: Vaccination Refusal

Calificado: Summative: Vaccination

SEMANA 6

Control Mechanisms

In module 6 of the course, you will learn about mechanisms involved in controlling epidemics. In these lectures, we will discuss what control mechanisms are trying to do, such as breaking the chain of transmission, and many ways by which animals and humans attempt to achieve control. These means include pharmaceutical and non-pharmaceutical interventions, appearing at individual or population levels. We will describe examples of great successes in eradication, and the reasons why control efforts fail.

10 videos, 1 lectura

Reading: Module Objectives: Control Mechanisms
Vídeo: Social Challenges to Eradication
Vídeo: Non-pharmaceutical Interventions: Animals
Vídeo: Non-pharmaceutical Interventions: Humans 1
Vídeo: Non-pharmaceutical Interventions: Humans 2
Vídeo: Behavioral Avoidance
Vídeo: Controlling the Vector
Vídeo: Consequences of Control
Vídeo: Vaccination Ethics
Vídeo: New Approaches to an Old Infection

Calificado: Summative: Control Mechanisms

SEMANA 7

Emergence

In module 7 of the course, we’ll look at so-called emerging infectious diseases. These are diseases that are causing new problems. They include infectious agents that are new to humanity, but also infectious agents that were once controlled and are now returning, particularly those that are evolving around formerly very effective public health tools like drugs and vaccines. This means much of the week involves a discussion of evolution. We will look at these emerging diseases and ask, where do they come from and what can be done about them? You will learn about new ideas for managing evolution, and some of the societal challenges involved. We will also look at the related question of how some diseases evolve to be nicer or nastier to their hosts.

7 videos, 1 lectura

Reading: Module Overview: Emergence
Vídeo: Re-emergence
Vídeo: Evolution General
Vídeo: Antibiotic and Drug Resistance
Vídeo: Management of Resistance
Vídeo: Behavioral And Economic Impact
Vídeo: Evolution of Virulence

Calificado: Summative: Emergence

SEMANA 8

Global Health

In this final module we explore the global context of epidemics. The world is rapidly changing with the global population increasing and the speed of travel and extent of globalization piling on the pressure of infectious diseases. In this week we set out first to explore a textbook example of disease shaped by the conditions presented by modern living: the disease SARS. We will see how high density living in cities coupled with links to wildlife diseases through markets can create a pandemic. We then explore traditional methods of disease surveillance and then more recent ones afforded to us by the web and networks made possible through google, twitter and other social media. Important to this global view is human behavior, our evolving culture and health. We will also consider emerging disease and the global pattern of diseases across our recent history and how from our earliest beginnings of global travellers we have affected the spread of diseases. Finally, we discuss disease of our food plants and how models of disease spread are developed to promote better global health. As a postscript to the course we ask the questions, so beloved of modern media, could we become zombies?

9 videos, 1 lectura

Reading: Module Overview: Global Health
Vídeo: Disease Surveillance - Classical
Vídeo: Disease Surveillance - Digital
Vídeo: Culture and Health
Vídeo: Emerging Disease Issues
Vídeo: Crop Diseases and Food Security
Vídeo: Global Pattern of Parasite Biodiversity
Vídeo: Models of Infectious Diseases
Vídeo: Zombies

Calificado: Summative: Global Health

Ask Us Anything Videos

The videos accessible in this module are responses to questions that have been posed in previous sessions of this course. We invite you to look around here as an additional resource to answer questions you might have yourself or explore topics that pique your interest.

36 videos

Vídeo: What Does It Mean to Be Infectious?
Vídeo: What is the Impact of Prior Infections on Susceptibility to New Pathogens?
Vídeo: What Ended the Plague? What Can We Learn About Pandemics?
Vídeo: Can Behavior Contribute to Susceptibility?
Vídeo: Marilyn Roosinck and What’s Different about Plant Epidemiology?
Vídeo: Can Plants be Vectors of Disease?
Vídeo: What are Other Determinants of Susceptibility?
Vídeo: Can Pathogens Change Host Function?
Vídeo: Immune System Conflict
Vídeo: Eric Harvill and What is the Whole Micro-Biome, Pro-Biotic, Good Bacteria Thing?
Vídeo: Why Can't Our Antibodies Mutate Like Antigens?
Vídeo: How Does Microbiome Exchange Therapy Work?
Vídeo: What are the Best Strategies to Combat Multi-Species Infections?
Vídeo: How Relevant is the Concept of Critical Community Size?
Vídeo: Isabella Catadori and the Translation of Her Lab Work into the Field
Vídeo: Examples of Co-Infections and How They Change Epidemiology of Human Infections
Vídeo: Super-Shedders v. Super Spreaders and the Pareto Principle
Vídeo: The Role of Social Media in Epidemiology and how Information is Disseminated
Vídeo: Dr. Vivek Kapur and What Do We Need to Know about Development and Implementation of New Vaccines?
Vídeo: Why Don't We Have Vaccines for Everything?
Vídeo: Why Don't We Use Targeted Vaccinations?
Vídeo: What Are the Benefits of So-Called Gain-of-Function Experiments?
Vídeo: Dr. Moriah Szpara and How/Why do viruses like Varicella and Herpes Re-activate Themselves?
Vídeo: What are the Challenges to the Eradication of Pathogens and Setting Eradication as a Goal?
Vídeo: How Does Stress Affect Susceptibility and the Expression of Disease?
Vídeo: Has there been a Collective Change in Human Behavior in Response to Sexually Transmitted Diseases?
Vídeo: What can we do to minimize selection for resistance in vectors?
Vídeo: Genetic engineering of vectors? pt.1
Vídeo: Genetic engineering of vectors? pt.2
Vídeo: What is the role of climate change in disease emergence?
Vídeo: What can we learn from antibiotic and vaccine use in agriculture?
Vídeo: Dr. Craig Cameron and What do We Mean by 'Antivirals?'
Vídeo: What is it About Polio?
Vídeo: What About the One Health Concept?
Vídeo: What is the Next Big Thing?

Compromiso	20 hours of videos and quizzes
Idioma	English
Cómo aprobar	Aprueba todas las tareas calificadas para completar el curso.
Calificaciones del usuario	4.7 estrellas Calificación promedio del usuario 4.7Ve los que los estudiantes dijeron

Epidemics - the Dynamics of Infectious Diseases

Epidemics - the Dynamics of Infectious Diseases