Acerca de este Curso
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A big welcome to “Bioinformatics: Introduction and Methods” from Peking University! In this MOOC you will become familiar with the concepts and computational methods in the exciting interdisciplinary field of bioinformatics and their applications in biology, the knowledge and skills in bioinformatics you acquired will help you in your future study and research. Course materials are available under the CC BY-NC-SA License....
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Cursos 100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
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Fechas límite flexibles

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Sugerido: 1-2 hours/week

Aprox. 18 horas para completar
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English

Subtítulos: English
Globe

Cursos 100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
Calendar

Fechas límite flexibles

Restablece las fechas límite en función de tus horarios.
Clock

Sugerido: 1-2 hours/week

Aprox. 18 horas para completar
Comment Dots

English

Subtítulos: English

Programa - Qué aprenderás en este curso

1

Sección
Clock
2 horas para completar

Introduction and History of Bioinformatics

Welcome to “Bioinformatics: Introduction and Methods! Upon completion of this module you will be able to: become familiar with the essential concepts of bioinformatics; explore the history of this young area; experience how rapidly bioinformatics is growing. Our supplementary materials will give you a better understanding of the course lectures through they are not required in quizzes or exams...
Reading
4 videos (Total: 69 min), 2 readings, 1 quiz
Video4 videos
History of Bioinformatics30m
Bioinformatics in Mainland China8m
About This Course9m
Reading2 lecturas
Readings10m
Slides10m
Quiz1 ejercicio de práctica
Introduction and History of Bioinformatics20m

2

Sección
Clock
2 horas para completar

Sequence Alignment

Upon completion of this module, you will be able to: describe dynamic programming based sequence alignment algorithms; differentiate between the Needleman-Wunsch algorithm for global alignment and the Smith-Waterman algorithm for local alignment; examine the principles behind gap penalty and time complexity calculation which is crucial for you to apply current bioinformatic tools in your research; experience the discovery of Smith-Waterman algorithm with Dr. Michael Waterman himself....
Reading
7 videos (Total: 99 min), 2 readings, 1 quiz
Video7 videos
Global Alignment by Dynamic Programming14m
From Global to Local6m
Alignment with Affine Gap Penalty and Calculation of Time Complexity of The Needleman-Wunsch Algorithm6m
Interview with M. S. Waterman Waterman29m
Supplement on Homology & Similarity, Similarity Matrix and Dot Matrix (English Subtitles)10m
Student Presentation (English Subtitles)18m
Reading2 lecturas
Readings10m
Slides10m
Quiz1 ejercicio de práctica
Sequence Alignment18m

3

Sección
Clock
1 hora para completar

Sequence Database Search

Upon completion of this module, you will be able to: become familiar with sequence databse search and most common databases; explore the algoritm behind BLAST and the evaluation of BLAST results; ajdust BLAST parameters base on your own research project....
Reading
3 videos (Total: 41 min), 2 readings, 1 quiz
Video3 videos
BLAST Algorithm: A Primer13m
Student Presentation (English Subtitles)15m
Reading2 lecturas
Readings10m
Slides10m
Quiz1 ejercicio de práctica
Sequence Database Search10m

4

Sección
Clock
1 hora para completar

Markov Model

Upon completion of this module, you will be able to: recognize state transitions, Markov chain and Markov models; create a hidden Markov model by yourself; make predictuions in a real biological problem with hidden Markov model....
Reading
4 videos (Total: 47 min), 2 readings, 1 quiz
Video4 videos
Hidden Markov Model11m
Predict with Hidden Markov Model10m
Student Presentation16m
Reading2 lecturas
Readings10m
Slides10m
Quiz1 ejercicio de práctica
Markov Model 14m

Instructores

Ge Gao 高歌, Ph.D.

Assistant Professor, Principle Investigator
Center for Bioinformatics, School of Life Science

Liping Wei 魏丽萍, Ph.D.

Professor, Director
Center for Bioinformatics, School of Life Sciences

Acerca de Peking University

Peking University is determined to make its education openly accessible to students in China and around the world. With over 3000 faculty members, Peking University offers excellence in teaching and learning. Founded in 1898, Peking University (PKU) was the first national comprehensive university in China. For the past 115 years, with its hundreds of thousands of outstanding alumni, Peking University has made prominent contributions in the humanities and sciences to further China's prosperity and progress....

Preguntas Frecuentes

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

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