Acerca de este Curso
100 % en línea

100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
Fechas límite flexibles

Fechas límite flexibles

Restablece las fechas límite en función de tus horarios.
Nivel principiante

Nivel principiante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 7 weeks of study, 2-4 hours per week...
Idiomas disponibles

Inglés (English)

Subtítulos: Inglés (English)...
100 % en línea

100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
Fechas límite flexibles

Fechas límite flexibles

Restablece las fechas límite en función de tus horarios.
Nivel principiante

Nivel principiante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 7 weeks of study, 2-4 hours per week...
Idiomas disponibles

Inglés (English)

Subtítulos: Inglés (English)...

Programa - Qué aprenderás en este curso

Semana
1
Horas para completar
2 horas para completar

Introduction & Shortcomings of Current Approaches

This module introduces you to the course, outlines the shortcomings of current toxicity testing approaches, and shows how EBT can help to overcome these shortcomings....
Reading
9 videos (Total: 66 min), 3 readings, 1 quiz
Video9 videos
Introduction to the Course14m
Introduction5m
Shortcoming No. 1: Narrative Reviews7m
Shortcoming No. 2: Bias in Reviews7m
Shortcoming No. 3: Evidence Writing4m
Shortcoming No. 4: External Validity10m
Shortcoming No. 5: Assessing New Methods5m
Shortcoming No. 6: Inadequate Reporting7m
Reading3 lecturas
Letter to Learners10m
Course Learning Objectives10m
Supporting reading10m
Quiz1 ejercicio de práctica
Practice Quiz 18m
Semana
2
Horas para completar
3 horas para completar

History and Causation

This module explains how evidence-based toxicology originated and describes the driving forces for the initiative. In the second lesson, you will learn how to distinguish between correlation and causation as well as the main problems with drawing conclusions on the basis of correlations. The Bradford Hill criteria are introduced, along with examples for each criterion. You will also learn about mechanistic toxicology and mechanistic validation....
Reading
11 videos (Total: 138 min), 2 readings, 1 quiz
Video11 videos
Personal First Exposures to Evidence-Based Medicine21m
The Start of EBT16m
The First Conference 2007 to the Start of the EBT Collaboration 201114m
The Evidence-Based Toxicology Collaboration (EBTC)13m
Introduction Causation vs. Correlation18m
The Hill Principles of Epidemiology and their Relation to Toxicology16m
The Problem of Causation in Toxicology16m
Biomarker Concept in Mechanistic Toxicology4m
Mechanistic Validation4m
The Future of Causation in Complex Systems9m
Reading2 lecturas
Supporting reading10m
Supporting reading10m
Quiz1 ejercicio de práctica
Practice Quiz 210m
Semana
3
Horas para completar
3 horas para completar

Systematic Review and Meta-Analysis

This module shows how to perform systematic reviews and meta-analyses. You will learn the history of both methods and will receive step-by-step instructions on how to perform systematic reviews and meta-analyses using examples from the research activities of the instructors. ...
Reading
8 videos (Total: 101 min), 2 readings, 2 quizzes
Video8 videos
Systematic Reviews: Definition and Principles26m
Systematic Reviews - Protocol Development15m
Systematic Reviews - Protocol Development (Part 2)19m
History5m
Meta-analysis Guidelines7m
Meta-analysis Protocol, Part 110m
Meta-analysis Protocol, Part 212m
Reading2 lecturas
Supporting reading10m
Supporting reading10m
Quiz2 ejercicios de práctica
Practice Quiz 36m
Mid-course exam30m
Semana
4
Horas para completar
2 horas para completar

Risk of Bias & Application to Test Methods Comparison

This module teaches you about possible biases that can be introduced at different stages of research. Each bias is explained with examples, including solutions for overcoming those biases. The second lesson covers systematic review of the zebrafish embryotoxicity test as a case study conducted by the Evidence-based Toxicology Collaboration (EBTC). You will go through all of the steps of the systematic review again to imprint the knowledge from module 3, but this systematic review will be related to a toxicological method....
Reading
8 videos (Total: 94 min), 2 readings, 1 quiz
Video8 videos
Introduction to Risk of Bias Concept in Critical Appraisal of Studies26m
Examples for Risk of Bias Tools 1: Cochrane Collboration4m
Examples for Risk of Bias Tools 2: SYRCLE's RoB Tool5m
Examples of Risk of Bias Tools 3: National Institute for Environmental Health Sciences (NIEHS) - OHAT12m
Quality Assessment in Evidence-Based Toxicology7m
Evidence-Based Toxicology (EBT) and Evidence-Based Toxicology Collaboration (EBTC)11m
Zebrafish Systematic Review22m
Reading2 lecturas
Supporting reading10m
Supporting reading10m
Quiz1 ejercicio de práctica
Practice Quiz 410m

Instructores

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Thomas Hartung

Professor
Environmental Health and Engineering
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Lena Smirnova

Research Associate
Center for Alternatives to Animal Testing

Acerca de Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world....

Preguntas Frecuentes

  • Una vez que te inscribes para obtener un Certificado, tendrás acceso a todos los videos, cuestionarios y tareas de programación (si corresponde). Las tareas calificadas por compañeros solo pueden enviarse y revisarse una vez que haya comenzado tu sesión. Si eliges explorar el curso sin comprarlo, es posible que no puedas acceder a determinadas tareas.

  • Cuando compras un Certificado, obtienes acceso a todos los materiales del curso, incluidas las tareas calificadas. Una vez que completes el curso, se añadirá tu Certificado electrónico a la página Logros. Desde allí, puedes imprimir tu Certificado o añadirlo a tu perfil de LinkedIn. Si solo quieres leer y visualizar el contenido del curso, puedes participar del curso como oyente sin costo.

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