Acerca de este Curso
4.8
162 calificaciones
34 revisiones
Programa Especializado
100 % en línea

100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
Fechas límite flexibles

Fechas límite flexibles

Restablece las fechas límite en función de tus horarios.
Nivel principiante

Nivel principiante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 3 hours/week...
Idiomas disponibles

Inglés (English)

Subtítulos: Inglés (English), Chino (simplificado)

Habilidades que obtendrás

AlgorithmsPython ProgrammingWhole Genome SequencingDynamic Programming
Programa Especializado
100 % en línea

100 % en línea

Comienza de inmediato y aprende a tu propio ritmo.
Fechas límite flexibles

Fechas límite flexibles

Restablece las fechas límite en función de tus horarios.
Nivel principiante

Nivel principiante

Horas para completar

Aprox. 15 horas para completar

Sugerido: 3 hours/week...
Idiomas disponibles

Inglés (English)

Subtítulos: Inglés (English), Chino (simplificado)

Programa - Qué aprenderás en este curso

Semana
1
Horas para completar
4 horas para completar

Week 1: Introduction to Genome Sequencing

<p>Welcome to class!</p><p>This course will focus on two questions at the forefront of modern computational biology, along with the algorithmic approaches we will use to solve them in parentheses:</p><ol><li>Weeks 1-2: How Do We Assemble Genomes? (<i>Graph Algorithms</i>)</li><li>How Do We Sequence Antibiotics? (<i>Brute Force Algorithms</i>)</li></ol><p>Each of the two chapters of content in the class is accompanied by a Bioinformatics Cartoon created by talented San Diego artist Randall Christopher and serving as a chapter header in the Specialization's bestselling <a href="http://bioinformaticsalgorithms.com" target="_blank">print companion</a>. You can find the first chapter's cartoon at the bottom of this message. What does a time machine trip to 1735, a stack of newspapers, a jigsaw puzzle, and a giant ant invading a riverside city have to do with putting together a genome? Start learning today to find out!</p><p><img src="https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter4_final_lr.jpg" title="Image: https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter4_final_lr.jpg" width="528"></p>...
Reading
8 videos (Total 36 min), 2 readings, 3 quizzes
Video8 videos
FIELD TRIP!4m
What Is Genome Sequencing?6m
Exploding Newspapers4m
The String Reconstruction Problem3m
String Reconstruction as a Hamiltonian Path Problem3m
String Reconstruction as an Eulerian Path Problem5m
Similar Problems with Different Fates 3m
Reading2 lecturas
Course Details10m
Week 1 FAQs (Optional)0
Quiz1 ejercicio de práctica
Week 1 Quiz15m
Semana
2
Horas para completar
3 horas para completar

Week 2: Applying Euler's Theorem to Assemble Genomes

<p>Welcome to Week 2 of class!</p> <p>This week in class, we will see how a 300 year-old mathematical theorem will help us assemble a genome from millions of tiny pieces of DNA.</p>...
Reading
5 videos (Total 28 min), 1 reading, 3 quizzes
Video5 videos
Euler's Theorem 6m
Assembling Read-Pairs 8m
De Bruijn Graphs Face Harsh Realities of Assembly 4m
Returning to Konigsberg 1m
Reading1 lectura
Week 2 FAQs (Optional)0
Quiz1 ejercicio de práctica
Week 2 Quiz15m
Semana
3
Horas para completar
4 horas para completar

Week 3: Sequencing Antibiotics

<p>Welcome to Week 3 of class!</p> <p>This week, we begin a new chapter, titled "How Do We Sequence Antibiotics?" &nbsp;In this chapter, we will learn&nbsp;how to determine the amino acid sequences making up antibiotics using brute force algorithms.</p> <p>Below is this week's Bioinformatics Cartoon.</p> <p><img src="https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter2_final.jpg" title="Image: https://d396qusza40orc.cloudfront.net/bioinformatics%2Fimages%2Fchapter2_final.jpg" width="528"></p>...
Reading
5 videos (Total 27 min), 1 reading, 3 quizzes
Video5 videos
How Do Bacteria Make Antibiotics? 8m
Sequencing Antibiotics by Shattering Them into Pieces 4m
A Brute Force Algorithm for Cyclopeptide Sequencing 3m
Cyclopeptide Sequencing with Branch and Bound 6m
Reading1 lectura
Week 3 FAQs (Optional)0
Quiz1 ejercicio de práctica
Week 3 Quiz15m
Semana
4
Horas para completar
3 horas para completar

Week 4: From Ideal to Real Spectra for Antibiotics Sequencing

<p>Welcome to Week 4 of class!</p> <p>Last week, we discussed how to sequence an antibiotic peptide from an ideal spectrum. This week, we will see how to develop more sophisticated algorithms for antibiotic peptide sequencing that are able to handle spectra with many false and missing masses.</p>...
Reading
4 videos (Total 18 min), 1 reading, 3 quizzes
Video4 videos
From 20 to More than 100 Amino Acids 2m
The Spectral Convolution Saves the Day 6m
The Truth About Spectra 2m
Reading1 lectura
Week 4 FAQs (Optional)0
Quiz1 ejercicio de práctica
Week 4 Quiz15m
4.8
34 revisionesChevron Right
Dirección de la carrera

50%

comenzó una nueva carrera después de completar estos cursos
Beneficio de la carrera

83%

consiguió un beneficio tangible en su carrera profesional gracias a este curso

Principales revisiones

por SVJan 10th 2017

Great course to explore a bit of Bioinformatics for those with no background in Bioinformatics. I love the way the content has been provided, its interactivity increases the interest in the course.

por MPDec 8th 2017

I like the real-world tasks, especially the assembly on the final exam. Some of the programming tasks, such as the antibiotic noisy spectrum assembly, are challenging (which is good).

Instructores

Avatar

Pavel Pevzner

Professor
Department of Computer Science and Engineering
Avatar

Phillip Compeau

Visiting Researcher
Department of Computer Science & Engineering

Acerca de University of California San Diego

UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 10 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom—life is their laboratory....

Acerca del programa especializado Bioinformatics

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all species on Earth? When you complete this Specialization, you will learn how to answer many questions in modern biology that have become inseparable from the computational approaches used to solve them. You will also obtain a toolkit of existing software resources built on these computational approaches and that are used by thousands of biologists every day in one of the fastest growing fields in science. Although this Specialization centers on computational topics, you do not need to know how to program in order to complete it. If you are interested in programming, we feature an "Honors Track" (called "hacker track" in previous runs of the course). The Honors Track allows you to implement the bioinformatics algorithms that you will encounter along the way in dozens of automatically graded coding challenges. By completing the Honors Track, you will be a bioinformatics software professional! Learn more about the Bioinformatics Specialization (including why we are wearing these crazy outfits) by watching our introductory video. You can purchase the Specialization's print companion, Bioinformatics Algorithms: An Active Learning Approach, from the textbook website. Our first course, "Finding Hidden Messages in DNA", was named a top-50 MOOC of all time by Class Central!...
Bioinformatics

Preguntas Frecuentes

  • Una vez que te inscribes para obtener un Certificado, tendrás acceso a todos los videos, cuestionarios y tareas de programación (si corresponde). Las tareas calificadas por compañeros solo pueden enviarse y revisarse una vez que haya comenzado tu sesión. Si eliges explorar el curso sin comprarlo, es posible que no puedas acceder a determinadas tareas.

  • Cuando te inscribes en un curso, obtienes acceso a todos los cursos que forman parte del Programa especializado y te darán un Certificado cuando completes el trabajo. Se añadirá tu Certificado electrónico a la página Logros. Desde allí, puedes imprimir tu Certificado o añadirlo a tu perfil de LinkedIn. Si solo quieres leer y visualizar el contenido del curso, puedes auditar el curso sin costo.

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